The Long Life of Birds: The Rat-Pigeon Comparison Revisited
Magdalene K Montgomery, AJ Hulbert, William A Buttemer
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2011
The most studied comparison of aging and maximum lifespan potential (MLSP) among endotherms involves the 7-fold longevity difference between rats (MLSP 5y) and pigeons (MLSP 35y). A widely accepted theory explaining MLSP differences between species is the oxidative stress theory, which purports that reactive oxygen species (ROS) produced during mitochondrial respiration damage bio-molecules and eventually lead to the breakdown of regulatory systems and consequent death. Previous rat-pigeon studies compared only aspects of the oxidative stress theory and most concluded that the lower mitochondrial superoxide production of pigeons compared to rats was responsible for their much greater longevi..View full abstract
Awarded by Australian Research Council
This research was supported by funding from the Australian Research Council (DP8079261). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.