Misdiagnosis of HIV infection during a South African community-based survey: implications for rapid HIV testing
Tendesayi Kufa, Ayesha BM Kharsany, Cherie Cawood, David Khanyile, Lara Lewis, Anneke Grobler, Zawadi Chipeta, Alfred Bere, Mary Glenshaw, Adrian Puren
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY | JOHN WILEY & SONS LTD | Published : 2017
INTRODUCTION: We describe the overall accuracy and performance of a serial rapid HIV testing algorithm used in community-based HIV testing in the context of a population-based household survey conducted in two sub-districts of uMgungundlovu district, KwaZulu-Natal, South Africa, against reference fourth-generation HIV-1/2 antibody and p24 antigen combination immunoassays. We discuss implications of the findings on rapid HIV testing programmes. METHODS: Cross-sectional design: Following enrolment into the survey, questionnaires were administered to eligible and consenting participants in order to obtain demographic and HIV-related data. Peripheral blood samples were collected for HIV-related ..View full abstract
Awarded by US President's Emergency Plan for AIDS Relief (PEPFAR) through US CDC
Awarded by South African Medical Research Council - National Institutes of Health
This study was funded by the US President's Emergency Plan for AIDS Relief (PEPFAR) through the US CDC under terms of the co-operative agreement 3U2GGH000372-02 W1. ABMK is supported by a joint South African Medical Research Council - National Institutes of Health grant [R01HD083343]. The content is solely the responsibility of the authors and does not necessarily represent the official views of any of the funders.