Journal article

Factors affecting first-month adherence to antiretroviral therapy among HIV-positive adults in South Africa

Dikokole Maqutu, Temesgen Zewotir, Delia North, Kogieleum Naidoo, Anneke Grobler

African Journal of AIDS Research | NATL INQUIRY SERVICES CENTRE PTY LTD | Published : 2010

Abstract

This study explores the influence of baseline factors on first-month adherence to highly active antiretroviral therapy (HAART) among adults. The study design involved a review of routinely collected patient information in the CAPRISA AIDS Treatment (CAT) programme, at a rural and an urban clinic in KwaZulu-Natal Province, South Africa. The records of 688 patients enrolled in the CAT programme between June 2004 and September 2006 were analysed. Adherence was calculated from pharmacy records (pill counts) and patients were considered adherent if they had taken at least 95% of their prescribed drugs. Logistic regression was used to analyse the data and account for confounding factors. During th..

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Grants

Awarded by American National Institutes of Health (NIH)


Awarded by PEPFAR grant


Awarded by Fogarty International Center


Awarded by FOGARTY INTERNATIONAL CENTER


Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES


Funding Acknowledgements

CAPRISA was established in 2002 through a Comprehensive International Program of Research on AIDS (CIPRA) grant (AI51794) from the American National Institutes of Health (NIH), as a multi-institutional collaboration, incorporated as an independent non-profit AIDS research organisation. The NIH funded the development of the research infrastructure, including the data management, laboratory and pharmacy cores established through the CIPRA grant. A PEPFAR grant (1U2GPS001350) funded the care of the patients in the CAT programme. Dikokole Maqutu was supported by the Columbia University-Southern African Fogarty AIDS International Training and Research Programme (AITRP), funded by the Fogarty International Center (grant D43TW00231). We gratefully acknowledge all the patients in the CAT programme. We also thank all the staff who worked on treating patients in the programme and who helped with the data collection. Special thanks are extended to the pharmacists for collection of the pill-count data.