Association of serum lutein and zeaxanthin with quantitative measures of retinal vascular parameters
Neelam Kumari, Joanna Cher, Edwin Chua, Haslina Hamzah, Tien Yin Wong, Carol Y Cheung
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2018
To evaluate the association between serum carotenoids and quantitative measures of retinal vasculature in elderly Singapore Chinese subjects. The following details were collected in 128 healthy subjects: sociodemographics, lifestyle information, medical and drug history, and anthropometric measurements. Serum concentrations of carotenoids were estimated in fasting venous blood using high performance liquid chromatography. Retinal vascular parameters were quantitatively measured from retinal photographs using a computer-assisted program (Singapore I Vessel Assessment). The mean age of the population was 54.1 years (range 40 to 81 years). In multiple linear regression analysis, per SD decrease..View full abstract
This study was supported by Small Innovative grant I for the year 2012, awarded to NK by Alexandra Health Private Limited. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.