Journal article

Association of serum lutein and zeaxanthin with quantitative measures of retinal vascular parameters

Neelam Kumari, Joanna Cher, Edwin Chua, Haslina Hamzah, Tien Yin Wong, Carol Y Cheung

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2018

Abstract

To evaluate the association between serum carotenoids and quantitative measures of retinal vasculature in elderly Singapore Chinese subjects. The following details were collected in 128 healthy subjects: sociodemographics, lifestyle information, medical and drug history, and anthropometric measurements. Serum concentrations of carotenoids were estimated in fasting venous blood using high performance liquid chromatography. Retinal vascular parameters were quantitatively measured from retinal photographs using a computer-assisted program (Singapore I Vessel Assessment). The mean age of the population was 54.1 years (range 40 to 81 years). In multiple linear regression analysis, per SD decrease..

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