Neurococognitive and neuroimaging correlates of obesity and components of metabolic syndrome in bipolar disorder: a systematic review
Emre Bora, Roger S McIntyre, Aysegul Ozerdem
PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2019
BACKGROUND: Individuals with bipolar disorder (BD) have a higher prevalence of obesity and metabolic syndrome (MetS) compared with the general population. Obesity and MetS are associated with cognitive deficits and brain imaging abnormalities in the general population. Obesity and components of MetS might potentially associate with neuroimaging and neurocognitive findings in BD. METHODS: A literature search of studies investigating the association between obesity (and other components of MetS) and neurocognitive and neuroimaging findings in BD was conducted. In addition to a systematic review, a random-effects meta-analysis was conducted when sufficient data were available. RESULTS: Twenty-t..View full abstract
Awarded by Scientific and Technological Research Council of Turkey (TUBITAK)
Dr Bora is supported by The Scientific and Technological Research Council of Turkey (TUBITAK) BIDEB2232 fellowship. The authors would like to thank authors of La Montagna et al. (2017) for providing additional information.