Journal article

Neurococognitive and neuroimaging correlates of obesity and components of metabolic syndrome in bipolar disorder: a systematic review

Emre Bora, Roger S McIntyre, Aysegul Ozerdem

PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2019

Abstract

BACKGROUND: Individuals with bipolar disorder (BD) have a higher prevalence of obesity and metabolic syndrome (MetS) compared with the general population. Obesity and MetS are associated with cognitive deficits and brain imaging abnormalities in the general population. Obesity and components of MetS might potentially associate with neuroimaging and neurocognitive findings in BD. METHODS: A literature search of studies investigating the association between obesity (and other components of MetS) and neurocognitive and neuroimaging findings in BD was conducted. In addition to a systematic review, a random-effects meta-analysis was conducted when sufficient data were available. RESULTS: Twenty-t..

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University of Melbourne Researchers