Parkinson's disease prevalence and the association with rurality and agricultural determinants
Darshini Ayton, Scott Ayton, Anna L Barker, Ashley I Bush, Narelle Warren
PARKINSONISM & RELATED DISORDERS | ELSEVIER SCI LTD | Published : 2019
INTRODUCTION: Parkinson's disease prevalence has been associated with rurality and pesticide use in studies throughout the world. Here, Parkinson's disease (PD) medication usage was used to estimate prevalence in 79 urban and rural localities in Victoria, Australia (5.3 million people). METHODS: An ecological study design was used to determine whether PD medication usage, as a reporter of PD diagnosis, differed between 79 regions in Victoria, and whether variance in PD prevalence was associated with population demographics using multiple regression. Cluster formation probability was calculated using Monte Carlo modelling. The association between agricultural production and PD prevalence was ..View full abstract
This study was directly supported by funds from Parkinson's Victoria. Additional support was obtained from Australian Research Council, the Australian National Health & Medical Research Council, and Operational Infrastructure Support Victorian State Government.