Journal article
Effects of long-term exercise therapy on knee joint structure in people with knee osteoarthritis: A systematic review and meta-analysis
A Van Ginckel, M Hall, F Dobson, P Calders
Seminars in Arthritis and Rheumatism | W B SAUNDERS CO-ELSEVIER INC | Published : 2019
Abstract
Objective: To investigate effects of long-term exercise therapy for people with knee osteoarthritis (OA)on radiographic disease severity and cartilage integrity (primary outcomes)as well as severity of bone marrow lesions (BMLs), synovitis and/or effusion (secondary outcomes). Methods: We sourced randomized controlled trials in people with clinical and/or radiographic OA investigating the effect of land-based exercise therapy of > 6 months on radiographic disease severity and magnetic resonance imaging outcomes of cartilage integrity (morphology or composition)as well as BML, synovitis and/or effusion severity, when compared to no exercise. Two independent reviewers extracted data and assess..
View full abstractGrants
Awarded by Horizon 2020 Framework Programme
Funding Acknowledgements
The authors gratefully acknowledge Foeke Blauwblomme and Robin Claeys for their assistance in data collection. AVG is supported by a FWO (Pegasus)2 Marie-Sklodowska Curie Fellowship (Horizon 2020 Grant #665501). MH is supported by a Sir Randal Heymanson Research Fellowship from The University of Melbourne. The funding sources had no involvement in the design, conduct, analysis or reporting of these findings.