Journal article

Assessing the cost-effectiveness of a routine versus an extensive laboratory work-up in the diagnosis of anaemia in Dutch general practice

Michelle MA Kip, Annemarie Schop, Karlijn Stouten, Soraya Dekker, Geert-Jan Dinant, Hendrik Koffijberg, Patrick JE Bindels, Maarten J IJzerman, Mark-David Levin, Ron Kusters

ANNALS OF CLINICAL BIOCHEMISTRY | SAGE PUBLICATIONS INC | Published : 2018

Abstract

Background Establishing the underlying cause of anaemia in general practice is a diagnostic challenge. Currently, general practitioners individually determine which laboratory tests to request (routine work-up) in order to diagnose the underlying cause. However, an extensive work-up (consisting of 14 tests) increases the proportion of patients correctly diagnosed. This study investigates the cost-effectiveness of this extensive work-up. Methods A decision-analytic model was developed, incorporating all societal costs from the moment a patient presents to a general practitioner with symptoms suggestive of anaemia (aged ≥ 50 years), until the patient was (correctly) diagnosed and treated in pr..

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