Journal article

Bond Graph Representation of Chemical Reaction Networks

Peter Gawthrop, Edmund J Crampin

IEEE TRANSACTIONS ON NANOBIOSCIENCE | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | Published : 2018

Abstract

The Bond Graph approach and the Chemical Reaction Network approach for modeling the biomolecular systems were developed independently. This paper brings together the two approaches by providing a bond graph interpretation of the chemical reaction network concept of complexes. Both closed and open systems are discussed. The method is illustrated using a simple enzyme-catalyzed reaction and a trans-membrane transporter.

University of Melbourne Researchers

Grants

Funding Acknowledgements

Peter Gawthrop would like to thank the Melbourne School of Engineering for its support via a Professorial Fellowship. The authors would like to thank Ivo Siekmann for alerting them to [18]-[20] and the anonymous reviewers for helpful comments on the manuscript.