Journal article

Virus-virus interactions and host ecology are associated with RNA virome structure in wild birds

Michelle Wille, John-Sebastian Eden, Mang Shi, Marcel Klaassen, Aeron C Hurt, Edward C Holmes

Molecular Ecology | WILEY | Published : 2018


Little is known about the factors that shape the ecology of RNA viruses in nature. Wild birds are an important case in point, as other than influenza A virus, avian samples are rarely tested for viruses, especially in the absence of overt disease. Using bulk RNA-sequencing ("meta-transcriptomics"), we revealed the viral diversity present in Australian wild birds through the lens of the ecological factors that may determine virome structure and abundance. A meta-transcriptomic analysis of four Anseriformes (waterfowl) and Charadriiformes (shorebird) species sampled in temperate and arid Australia revealed the presence of 27 RNA virus genomes, 18 of which represent newly described species. The..

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