Journal article

Diagnostic yield of pleural fluid cytology in malignant effusions: an Australian tertiary centre experience

Paula Loveland, Micheal Christie, Gary Hammerschlag, Louis Irving, Daniel Steinfort

Internal Medicine Journal | WILEY | Published : 2018

Abstract

BACKGROUND: Timely diagnosis of malignant pleural effusions is critical to guide prognosis and management decisions. Cytological analysis of pleural fluid has been the first-line diagnostic test for many decades, with highly variable reported sensitivities of 40-90%. Its diagnostic accuracy in modern practice in Australia needs to be understood. AIMS: To determine the diagnostic yield of pleural fluid cytology for the detection of malignant pleural effusions and to determine the aetiologies of pleural effusions at our centre. METHODS: The study involved the retrospective chart review of all pleural fluid samples submitted for cytological analysis at a tertiary referral centre in Melbourne, A..

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