Journal article
Characterization of staphylococcal cassette chromosome mec elements from methicillin-resistant Staphylococcus pseudintermedius infections in Australian animals
KA Worthing, S Schwendener, V Perreten, S Saputra, GW Coombs, S Pang, MR Davies, S Abraham, DJ Trott, JM Norris
Msphere | AMER SOC MICROBIOLOGY | Published : 2018
Abstract
We examined the oxacillin resistance phenotype and genomic structure of staphylococcal cassette chromosome mec (SCCmec) elements from 77 veterinary methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates. Isolates were characterized by oxacillin broth microdilution, whole-genome sequencing, and bioformatics analysis. Five previously described SCCmec elements, and a sixth novel element, were identified: SCCmec III (also known as II-III), ΨSCCmec57395' and SCCmecNA45 (a SCCmec VII variant), all previously described in MRSP, and SCCmec IVg and SCCmec VT' previously described in both methicillin-resistant Staphylococcus aureus (MRSA) and MRSP. The sixth element was novel and found ..
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Awarded by Institute of Veterinary Bacteriology, University of Bern
Funding Acknowledgements
The collection of the 77 MRSP isolates was supported by Zoetis Pty Ltd. and the Australian Research Council-Linkage Grant (grant number LP130100736). Sequencing of Psi SCCmec<INF>KW21</INF> was supported by internal funds of the Institute of Veterinary Bacteriology of the University of Bern, Bern, Switzerland.