Journal article
Thirteen-Year Outcomes in Very Preterm Children Associated with Diffuse Excessive High Signal Intensity on Neonatal Magnetic Resonance Imaging
IM Mürner-Lavanchy, H Kidokoro, DK Thompson, LW Doyle, JLY Cheong, RW Hunt, TE Inder, PJ Anderson
Journal of Pediatrics | MOSBY-ELSEVIER | Published : 2019
Abstract
Objective: To investigate the association between white matter diffuse excessive high signal intensity (DEHSI) on neonatal magnetic resonance imaging in very preterm infants and neurobehavioral outcomes at the age of 13 years. Study design: Magnetic resonance images of very preterm children (<30 weeks gestational age or <1250 g birth weight) were evaluated at term-equivalent age with DEHSI classified into 5 grades. Additionally, visibility of the posterior periventricular crossroads was assessed. General intelligence, memory, attention, executive function, motor abilities, and behavior were examined in 125 children at age 13 years and related to DEHSI grades using linear regression. Results:..
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Awarded by State Government of Victoria
Funding Acknowledgements
Supported by Australia's National Health and Medical Research Council, including the Centre for Clinical Research Excellence (546519), Center for Research Excellence (1060733), Project Grants (237117 and 491209), Senior Research Fellowship (1081288 [to P.A.]), Career Development Fellowship (1085754 [to D.T.] and 1141354 [to J.C.]), and Early Career Fellowship (1012236 [to D.T.] and 1053787 [to J.C.]). Also supported by the Victorian Government's Operational Infrastructure Support Program and the US National Institutes of Health (HD058056). The authors have no conflicts of interest to disclose.