Journal article
Clinical presentation and therapeutic management of venous thrombosis in young children: A retrospective analysis
A Chan, AWA Lensing, D Kubitza, G Brown, D Elorza, M Ybarra, J Halton, S Grunt, G Kenet, D Bonnet, A Santamaria, P Saracco, T Biss, F Climent, P Connor, J Palumbo, K Thelen, WT Smith, A Mason, I Adalbo Show all
Thrombosis Journal | BMC | Published : 2018
Abstract
Background: Venous thromboembolism (VTE) in young children is not well documented. Methods: Clinicians from 12 institutions retrospectively evaluated the presentation, therapeutic management, and outcome of VTE in children younger than 2 years seen in 2011-2016. Feasibility of recruiting these children in EINSTEIN-Jr. phase III, a randomized trial evaluating rivaroxaban versus standard anticoagulation for VTE, was assessed. Results: We identified 346 children with VTE, of whom 227 (65.6%) had central venous catheter-related thrombosis (CVC-VTE), 119 (34.4%) had non-CVC-VTE, and 156 (45.1%) were younger than 1 month. Of the 309 children who received anticoagulant therapy, 86 (27.8%) had a sho..
View full abstractGrants
Funding Acknowledgements
The study was funded by Bayer AG.