Journal article

Field Performance and Diagnostic Accuracy of a Low-Cost Instrument-Free Point-of-Care CD4 Test (Visitect CD4) Performed by Different Health Worker Cadres among Pregnant Women

Stanley Luchters, Karl Technau, Yasmin Mohamed, Matthew F Chersich, Paul A Agius, Minh D Pham, Mary L Garcia, James Forbes, Andrew Shepherd, Ashraf Coovadia, Suzanne M Crowe, David A Anderson

Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2019


Measuring CD4 counts remains an important component of HIV care. The Visitect CD4 is the first instrument-free low-cost point-of-care CD4 test with results interpreted visually after 40 min, providing a result of ≥350 CD4 cells/mm3 The field performance and diagnostic accuracy of the test was assessed among HIV-infected pregnant women in South Africa. A nurse performed testing at the point-of-care using both venous and finger-prick blood, and a counselor and laboratory staff tested venous blood in the clinic laboratory (four Visitect CD4 tests/participant). Performance was compared to the mean CD4 count from duplicate flow cytometry tests on venous blood (FACSCalibur Trucount). In 2017, 156 ..

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University of Melbourne Researchers


Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This project was made possible through the generous support of the Saving Lives at Birth partners: the U.S. Agency for International Development, the Government of Norway, the Bill & Melinda Gates Foundation, Grand Challenges Canada, and the UK Government. It was prepared by Burnet Institute and does not necessarily reflect the views of the Saving Lives at Birth partners.We gratefully acknowledge the contribution to this work of the Victorian Operational Infrastructure Support Program received by the Burnet Institute. Support was also provided by the National Health and Medical Research Council of Australia through project grant GNT1063725 and by a Career Development Fellowship to S.L. Omega Diagnostics provided the Visitect CD4 tests free of charge for study purposes.