Journal article

Fermented foods, the gut and mental health: a mechanistic overview with implications for depression and anxiety

Hajara Aslam, Jessica Green, Felice N Jacka, Fiona Collier, Michael Berk, Julie Pasco, Samantha L Dawson

Nutritional Neuroscience | TAYLOR & FRANCIS LTD | Published : 2020


Mental disorders including depression and anxiety are often comorbid with gut problems, suggesting a bidirectional relationship between mental health and gut function. Several mechanisms might explain this comorbidity, such as inflammation and immune activation; intestinal permeability; perturbations in the hypothalamic-pituitary-adrenal axis; neurotransmitter/neuropeptide dysregulation; dietary deficiencies; and disturbed gut microbiome composition. The potential of modulating the microbiome-gut-brain axis, and subsequently mental health, through the use of functional foods, is an emerging and novel topic of interest. Fermented foods are considered functional foods due to their putative hea..

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Awarded by NHMRC Senior Principal Research Fellowship

Awarded by NHMRC Career Development Fellowship

Funding Acknowledgements

Michael Berk is supported by an NHMRC Senior Principal Research Fellowship (1059660).Felice N. Jacka has received Grant/Research support from the Brain and Behaviour Research Institute, the National Health and Medical Research Council (NHMRC), Australian Rotary Health, the Geelong Medical Research Foundation, the Ian Potter Foundation, Eli Lilly, Meat and Livestock Australia, Woolworths Limited, Fernwood Gyms, The Wilson Foundation, GMHBA and The University of Melbourne and has received speakers honoraria from Sanofi-Synthelabo, Janssen Cilag, Servier, Pfizer, Health Ed, Network Nutrition, Angelini Farmaceutica, Eli Lilly and Metagenics. She is supported by an NHMRC Career Development Fellowship (2) (#1108125). Felice Jacka is currently writing two books for commercial publication and has a personal belief that good diet quality is important for mental and brain health.