Journal article

The International Childhood Cancer Cohort Consortium (I4C): A research platform of prospective cohorts for studying the aetiology of childhood cancers

Gabriella Tikellis, Terence Dwyer, Ora Paltiel, Gary S Phillips, Stanley Lemeshow, Jean Golding, Kate Northstone, Andy Boyd, Sjurdur Olsen, Akram Ghantous, Zdenko Herceg, Mary H Ward, Siri E Haberg, Per Magnus, Jorn Olsen, Marin Strom, Somdat Mahabir, Rena R Jones, Anne-Louise Ponsonby, Jacqueline Clavel Show all

PAEDIATRIC AND PERINATAL EPIDEMIOLOGY | WILEY | Published : 2018

Abstract

BACKGROUND: Childhood cancer is a rare but leading cause of morbidity and mortality. Established risk factors, accounting for <10% of incidence, have been identified primarily from case-control studies. However, recall, selection and other potential biases impact interpretations particularly, for modest associations. A consortium of pregnancy and birth cohorts (I4C) was established to utilise prospective, pre-diagnostic exposure assessments and biological samples. METHODS: Eligibility criteria, follow-up methods and identification of paediatric cancer cases are described for cohorts currently participating or planning future participation. Also described are exposure assessments, harmonisati..

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Grants

Awarded by Murdoch Children's Research Institution


Awarded by UK Medical Research Council


Awarded by Wellcome Trust


Awarded by Innovation Fund Denmark


Awarded by NATIONAL CANCER INSTITUTE


Funding Acknowledgements

NIH intramural research programme (NCI, NICHD)-USA; National Children's Study-USA; Tour de Cure-Australia; The Children's Cancer Centre Foundation-Australia; Bluey Day Foundation-Australia; Baxter Family Foundation-Australia; The Rotary Club of North Brighton-Australia; Private philanthropic donations-Australia; Murdoch Children's Research Institution, Grant/Award Number: M1300049; The UK Medical Research Council and the Wellcome Trust, Grant/Award Number: 092731; The University of Bristol; The Maria Ascoli Foundation, Jerusalem, Israel; The Research Council of Norway; Innovation Fund Denmark, Grant/Award Number: 09-067124; Institut National du Cancer (INCa, Plan Cancer-EVA-INSERM, France)