Journal article
The International Childhood Cancer Cohort Consortium (I4C): A research platform of prospective cohorts for studying the aetiology of childhood cancers
G Tikellis, T Dwyer, O Paltiel, GS Phillips, S Lemeshow, J Golding, K Northstone, A Boyd, S Olsen, A Ghantous, Z Herceg, MH Ward, SE Håberg, P Magnus, J Olsen, M Ström, S Mahabir, RR Jones, AL Ponsonby, J Clavel Show all
Paediatric and Perinatal Epidemiology | WILEY | Published : 2018
DOI: 10.1111/ppe.12519
Open access
Abstract
Background: Childhood cancer is a rare but leading cause of morbidity and mortality. Established risk factors, accounting for <10% of incidence, have been identified primarily from case-control studies. However, recall, selection and other potential biases impact interpretations particularly, for modest associations. A consortium of pregnancy and birth cohorts (I4C) was established to utilise prospective, pre-diagnostic exposure assessments and biological samples. Methods: Eligibility criteria, follow-up methods and identification of paediatric cancer cases are described for cohorts currently participating or planning future participation. Also described are exposure assessments, harmonisati..
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Awarded by Wellcome Trust
Funding Acknowledgements
NIH intramural research programme (NCI, NICHD)-USA; National Children's Study-USA; Tour de Cure-Australia; The Children's Cancer Centre Foundation-Australia; Bluey Day Foundation-Australia; Baxter Family Foundation-Australia; The Rotary Club of North Brighton-Australia; Private philanthropic donations-Australia; Murdoch Children's Research Institution, Grant/Award Number: M1300049; The UK Medical Research Council and the Wellcome Trust, Grant/Award Number: 092731; The University of Bristol; The Maria Ascoli Foundation, Jerusalem, Israel; The Research Council of Norway; Innovation Fund Denmark, Grant/Award Number: 09-067124; Institut National du Cancer (INCa, Plan Cancer-EVA-INSERM, France)