Journal article

Use of anthropophilic culicid-based xenosurveillance as a proxy for Plasmodium vivax malaria burden and transmission hotspots identification

Joabi Nascimento, Vanderson S Sampaio, Stephan Karl, Andrea Kuehn, Anne Almeida, Sheila Vitor-Silva, Gisely Cardoso de Melo, Djane C Baia da Silva, Stefanie CP Lopes, Nelson F Fe, Jose B Pereira Lima, Maria G Barbosa Guerra, Paulo FP Pimenta, Quique Bassat, Ivo Mueller, Marcus VG Lacerda, Wuelton M Monteiro



Vector-borne diseases account for more than 17% of all infectious diseases, causing more than one million deaths annually. Malaria remains one of the most important public health problems worldwide. These vectors are bloodsucking insects, which can transmit disease-producing microorganisms during a blood meal. The contact of culicids with human populations living in malaria-endemic areas suggests that the identification of Plasmodium genetic material in the blood present in the gut of these mosquitoes may be possible. The process of assessing the blood meal for the presence of pathogens is termed 'xenosurveillance'. In view of this, the present work investigated the relationship between the ..

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Funding Acknowledgements

This work was supported by National Counsel of Technological and Scientific development (CNPq), Coordination for the Improvement of Higher Education Personnel (CAPES) and Research Support Foundation of Amazonas (FAPEAM) through PPSUS and PAPAC projects supported this study. Bill & Melinda Gates Foundation has also funded this study through TransEpi Project. PFPP and MVGL are level 1 fellows from CNPq. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.