Journal article

Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90 study

Nienke Legdeur, Maryam Badissi, Stephen F Carter, Sophie de Crom, Aleid van de Kreeke, Ralph Vreeswijk, Marijke C Trappenburg, Mardien L Oudega, Huiberdina L Koek, Jos P van Campen, Carolina JPW Keijsers, Chinenye Amadi, Rainer Hinz, Mark F Gordon, Gerald Novak, Jana Podhorna, Erik Serne, Frank Verbraak, Maqsood Yaqub, Arjan Hillebrand Show all

BMC GERIATRICS | BMC | Published : 2018

Abstract

BACKGROUND: The oldest-old (subjects aged 90 years and older) population represents the fastest growing segment of society and shows a high dementia prevalence rate of up to 40%. Only a few studies have investigated protective factors for cognitive impairment in the oldest-old. The EMIF-AD 90+ Study aims to identify factors associated with resilience to cognitive impairment in the oldest-old. In this paper we reviewed previous studies on cognitive resilience in the oldest-old and described the design of the EMIF-AD 90+ Study. METHODS: The EMIF-AD 90+ Study aimed to enroll 80 cognitively normal subjects and 40 subjects with cognitive impairment aged 90 years or older. Cognitive impairment was..

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