Journal article

Augmentation of the pulmonary arteries at or prior to the Fontan procedure is not associated with worse long-term outcomes: a propensity-matched analysis from the Australia-New Zealand Fontan Registry

Lauren Shearer, Robert N Justo, Supreet P Marathe, Kim Betts, Prem Venugopal, David S Winlaw, Andrew Bullock, Terry Robertson, Thomas L Gentles, David Celermajer, Yves d'Udekem, Nelson Alphonso

European Journal of Cardio-Thoracic Surgery | OXFORD UNIV PRESS INC | Published : 2019

Abstract

OBJECTIVES: Long-term data on the impact of pulmonary artery (PA) augmentation in patients who underwent the Fontan procedure are lacking. The aim of this study was to examine whether surgical or transcatheter PA augmentation at or prior to the Fontan procedure adversely affects the outcomes. METHODS: Data of 1436 patients from the Australia-New Zealand Fontan Registry (1975-2015) were analysed. Primary end point was death or Fontan failure. Cox regression with propensity score matching was used to determine risk or benefit conferred by PA augmentation. RESULTS: Forty-eight (3.3%) patients underwent PA augmentation following cavopulmonary shunt (surgical n = 14, balloon dilatation n = 16 and..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC


Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) Partnership Grant (1076849). Dr Y. d'U. is a Clinical Practitioner Fellow of the NHMRC (1082186) and has received consulting fees from Merck Sharp, Dohme and Actelion.