A Comparative Review of Mixed Mammary Tumors in Mammals
Eman SA Saad, Jacqueline SY Lam, Awf A Al-Khan, Mourad Tayebi, Michael J Day, Samantha J Richardson, Janine A Danks
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA | SPRINGER/PLENUM PUBLISHERS | Published : 2019
Mixed tumors are characterized by the histological identification of two or more cell types. Commonly, a mixture of epithelial and myoepithelial cells is included in abundant stroma, which can consist of myxoid, chondroid or bony matrices. Spontaneously arising mixed tumors are rare lesions in the human breast but are common in human salivary glands and canine mammary glands. Subtle histopathological characteristics and overlapping attributes of malignant lesions with other benign lesions can lead to a diagnostic challenge. Mixed tumors can present as benign or malignant. While malignant mixed tumors are quite rare in the human breast they have a poor prognosis. Benign mixed mammary tumors o..View full abstract
This work was supported by an Australian Government Research Training Program Scholarship. This work was also funded by the Libyan Ministry of Higher Education, which awarded a scholarship to Eman S. A. Saad. Funding was given by the School of Health and Biomedical Sciences at RMIT University. This research arose from a previous grant from the Australian Companion Animal Health Foundation which was awarded to Janine A. Danks.