Characteristics and outcomes of patients with acute liver failure admitted to Australian and New Zealand intensive care units
Stephen Warrillow, Michael Bailey, David Pilcher, Alex Kazemi, Colin McArthur, Paul Young, Rinaldo Bellomo
INTERNAL MEDICINE JOURNAL | WILEY | Published : 2019
BACKGROUND: Knowledge about patients with acute liver failure (ALF) in Australia and New Zealand (ANZ) is lacking. AIMS: To evaluate whether the pattern of ALF would be similar to previous studies and whether, despite potentially low transplantation rates, mortality would be comparable. METHODS: We obtained data from the ANZ Intensive Care Society Adult Patient Database and the ANZ Liver Transplant Registry for 10 years commencing 2005 and analysed for patient outcomes. RESULTS: During the study period, 1 022 698 adults were admitted to intensive care units across ANZ, of which 723 had ALF. The estimated annual incidence of ALF over this period was 3.4/million people and increased over time ..View full abstract
The Medical Research Institute of New Zealand is supported by Independent Research Organisation Funding from the Health Research Council of New Zealand. This research was conducted during the tenure of a Health Research Council of New Zealand Clinical Practitioner Research Fellowship held by P. Young.