Journal article

Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine

Stephan Beck, Alison M Berner, Graham Bignell, Maggie Bond, Martin J Callanan, Olga Chervova, Lucia Conde, Manuel Corpas, Simone Ecker, Hannah R Elliott, Silvana A Fioramonti, Adrienne M Flanagan, Ricarda Gaentzsch, David Graham, Deirdre Gribbin, Jose Afonso Guerra-Assuncao, Rifat Hamoudi, Vincent Harding, Paul L Harrison, Javier Herrero Show all

BMC MEDICAL GENOMICS | BMC | Published : 2018


BACKGROUND: Molecular analyses such as whole-genome sequencing have become routine and are expected to be transformational for future healthcare and lifestyle decisions. Population-wide implementation of such analyses is, however, not without challenges, and multiple studies are ongoing to identify what these are and explore how they can be addressed. METHODS: Defined as a research project, the Personal Genome Project UK (PGP-UK) is part of the global PGP network and focuses on open data sharing and citizen science to advance and accelerate personalized genomics and medicine. RESULTS: Here we report our findings on using an open consent recruitment protocol, active participant involvement, o..

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University of Melbourne Researchers


Awarded by Wellcome Trust

Awarded by National Institute for Health Research UCLH Biomedical Research Centre

Awarded by MRC

Funding Acknowledgements

PGP-UK gratefully acknowledges support from the UCL Cancer Institute Research Trust, the Frances and Augustus Newman Foundation, Dangoor Education, The Wellcome Trust (99148) and the National Institute for Health Research UCLH Biomedical Research Centre (BRC369/CN/SB/101310). The development of the GenoME app was supported by a donation from Michael Chowen CBE DL and Maureen Chowen. We also would like to acknowledge an award from the MRC Proximity to Discovery Industry Engagement Fund (530912) to facilitate access to the cloud-based computing infrastructure of Seven Bridges Genomics.