Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

Nai Yang Fu; Bhupinder Pal; Yunshun Chen; Felicity C Jackling; Michael Milevskiy; Francois Vaillant; Bianca D Capaldo; Fusheng Guo; Kevin H Liu; Anne C Rios; Nicholas Lim; Andrew J Kueh; David M Virshup; Marco J Herold; Haley O Tucker; Gordon K Smyth; Geoffrey J Lindeman; Jane E Visvader

Journal article

Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

Nai Yang Fu, Bhupinder Pal, Yunshun Chen, Felicity C Jackling, Michael Milevskiy, Francois Vaillant, Bianca D Capaldo, Fusheng Guo, Kevin H Liu, Anne C Rios, Nicholas Lim, Andrew J Kueh, David M Virshup, Marco J Herold, Haley O Tucker, Gordon K Smyth, Geoffrey J Lindeman, Jane E Visvader

Developmental Cell | CELL PRESS | Published : 2018

DOI: 10.1016/j.devcel.2018.10.001

University of Melbourne Researchers

Michael Milevskiy Author Medical Biology (W.E.H.I.)

Nai Fu Author Medical Biology (W.E.H.I.)

Francois Vaillant Author Medical Biology (W.E.H.I.)

Andrew Kueh Author Medical Biology (W.E.H.I.)

Marco Herold Author Medical Biology (W.E.H.I.)

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Fellowships

Funding Acknowledgements

We thank A. Chen and P. Jamieson for expert assistance and M. Ritchie for discussions. We are grateful to the Animal, Genotyping, FACS, Imaging and Histology facilities at WEHI. This work was supported by the Australian National Health and Medical Research Council (NHMRC) grants #1016701, #1054618, #1100807, #1113133; NHMRC IRIISS; the Victorian state government through VCA funding and Operational Infrastructure Support; and the Australian Cancer Research Foundation. N.Y.F. and A.C.R. were supported by a National Breast Cancer Foundation/Cure Cancer Australia Fellowship; G.K.S., and G.J.L. by NHMRC Fellowships #1058892, #1078730; and J.E.V. by NHMRC Fellowships #1037230 and 1102742.