Cognitive and Functional Assessment of Psychosis Stratification Study (CoFAPSS): Rationale, Design, and Characteristics
Scott R Clark, K Oliver Schubert, Andrew T Olagunju, Ellen Alexandra Lyrtzis, Bernhard T Baune
FRONTIERS IN PSYCHIATRY | FRONTIERS MEDIA SA | Published : 2018
Prediction of treatment response and illness trajectory in psychotic disorders including schizophrenia, bipolar affective disorder, schizoaffective disorder, and psychotic depression is difficult due to heterogeneity in presentation and outcome. Consequently, patients may receive prolonged ineffective treatments leading to functional decline, illness chronicity, and iatrogenic physical illness. One approach to addressing these problems is to stratify patients based on historical, clinical, and biological signatures. Such an approach has the potential to improve categorization resulting in better understanding of underlying mechanisms and earlier evidence-based treatment with reduced side eff..View full abstract
AO is supported by an Australian Government Research Training Program (RTP) Scholarship.