The TeMPO trial (treatment of meniscal tears in osteoarthritis): rationale and design features for a four arm randomized controlled clinical trial
James K Sullivan, James J Irrgang, Elena Losina, Clare Safran-Norton, Jamie Collins, Swastina Shrestha, Faith Selzer, Kim Bennell, Leslie Bisson, Angela T Chen, Courtney K Dawson, Alexandra B Gil, Morgan H Jones, Melissa A Kluczynski, Kathleen Lafferty, Jeffrey Lange, Emma C Lape, John Leddy, Aaron V Mares, Kurt Spindler Show all
BMC MUSCULOSKELETAL DISORDERS | BMC | Published : 2018
BACKGROUND: Meniscal tears often accompany knee osteoarthritis, a disabling condition affecting 14 million individuals in the United States. While several randomized controlled trials have compared physical therapy to surgery for individuals with knee pain, meniscal tear, and osteoarthritic changes (determined via radiographs or magnetic resonance imaging), no trial has evaluated the efficacy of physical therapy alone in these subjects. METHODS: The Treatment of Meniscal Tear in Osteoarthritis (TeMPO) Trial is a four-arm multi-center randomized controlled clinical trial designed to establish the comparative efficacy of two in-clinic physical therapy interventions (one focused on strengthenin..View full abstract
Awarded by National Institutes of Health
The TeMPO Trial is funded by the National Institutes of Health through a U01 grant (U01AR071658). The funding agency approved and commented on the broad elements of study design upon grant submission and review.