Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias
Shahzya Chaudhury, Caitriona O'Connor, Ana Canete, Joana Bittencourt-Silvestre, Evgenia Sarrou, Aine Prendergast, Jarny Choi, Pamela Johnston, Christine A Wells, Brenda Gibson, Karen Keeshan
Nature Communications | NATURE PUBLISHING GROUP | Published : 2018
Awarded by Cancer Research UK Glasgow Centre
Awarded by BSU facilities at the Cancer Research UK Beatson Institute
We acknowledge the technical assistance of Jennifer Cassels and the flow cytometry core funding from the Kay Kendell Leukaemia Fund and The Howat Foundation. We thank Karen Dunn for technical assistance with animal experiments and the Cancer Research UK Glasgow Centre (C596/A18076) and the BSU facilities at the Cancer Research UK Beatson Institute (C596/A17196). We thank Francesco Marchesi, Lynn Stevenson, Lynn Oxford and Frazer Bell (Veterinary Diagnostic Services, School of Veterinary Medicine, University of Glasgow) for their technical assistance with histology and immunohistochemistry. We thank Tyrone Chen for processing all relevant datasets. We thank all staff at the Paul O'Gorman Leukaemia Research Centre for helpful suggestions and advice. We thank support from Children with Cancer UK (to K.K.), the Howat foundation (to K.K., C.O'C., A.C.), Yorkhill Children Cancer, Yorkhill Children's Leukaemia Research Fund (to E.S., S.C., A.P.) and the Friends of Paul O' Gorman (to J.B.S.).