Age-dependent differences in the impact of paediatric traumatic brain injury on executive functions: A prospective study using susceptibility-weighted imaging
Christine Resch, Vicki A Anderson, Miriam H Beauchamp, Louise Crossley, Stephen JC Hearps, Caroline M van Heugten, Petra PM Hurks, Nicholas P Ryan, Cathy Catroppa
NEUROPSYCHOLOGIA | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019
Childhood and adolescence represent sensitive developmental periods for brain networks implicated in a range of complex skills, including executive functions (EF; inhibitory control, working memory, and cognitive flexibility). As a consequence, these skills may be particularly vulnerable to injuries sustained during these sensitive developmental periods. The present study investigated 1) whether age at injury differentially affects EF 6 months and 2 years after TBI in children aged 5-15 years, and 2) whether the association between brain lesions and EF depend on age at injury. Children with TBI (n = 105) were categorized into four age-at-injury groups based on previous studies and proposed t..View full abstract
This research was supported by the Victorian Neurotrauma Initiative and the Victorian Government Operational Infrastructure Scheme (No. CO6E1). The funding bodies did not play a role in the design of the study, collection, analysis and interpretation of the data, or writing of the manuscript.