Journal article

Evaluation of variability in human kidney organoids

Belinda Phipson, Pei X Er, Alexander N Combes, Thomas A Forbes, Sara E Howden, Luke Zappia, Hsan-Jan Yen, Kynan T Lawlor, Lorna J Hale, Jane Sun, Ernst Wolvetang, Minoru Takasato, Alicia Oshlack, Melissa H Little

Nature Methods | NATURE PUBLISHING GROUP | Published : 2019

Grants

Awarded by National Institute of Diabetes and Digestive and Kidney Diseases


Awarded by National Health and Medical Research Council of Australia (NHMRC)


Awarded by NHMRC


Awarded by NHMRC Postgraduate Scholarship


Awarded by Royal Australian College of Physicians Jacquot Award Recipient


Funding Acknowledgements

We thank A. Christ and G. Baillie at the Institute for Molecular Bioscience, The University of Queensland, for sequencing services. We acknowledge A. Mallett and S. Alexander for assistance in ethics applications and patient recruitment. We thank D. Vukcevic and G.K. Smyth for valuable discussion regarding random effects modeling, and J. Maksimovic for initial analysis and mapping of the patient RNA-seq data. This study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (grant no. DK107344) and National Health and Medical Research Council of Australia (NHMRC) (grant nos. GNT1041277, GNT1100970, GNT1098654). The Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program. M.H.L. is an NHMRC Senior Principal Research Fellow. A.O. is an NHMRC Career Development Fellow (grant no. GNT1126157). T.A.F. is an NHMRC Postgraduate Scholarship (grant no. GNT1114409) and Royal Australian College of Physicians Jacquot Award Recipient (grant no. APP1114409).