Journal article
Pilot field trial of the EG95 vaccine against ovine cystic echinococcosis in Rio Negro, Argentina: 8 years of work
E Larrieu, G Mujica, D Araya, JL Labanchi, M Arezo, E Herrero, G Santillán, K Vizcaychipi, L Uchiumi, JC Salvitti, C Grizmado, A Calabro, G Talmon, L Sepulveda, JM Galvan, M Cabrera, M Seleiman, P Crowley, G Cespedes, M García Cachau Show all
Acta Tropica | ELSEVIER SCIENCE BV | Published : 2019
Abstract
Cystic echinococcosis (CE) is endemic in the Rio Negro province of Argentina. After 30 years of control using praziquantel in dogs the transmission rate to humans and sheep has decreased significantly, however transmission persists. The objective of the study was to assess the inclusion of the EG95 for sheep in the control program and to determine the vaccine's operative feasibility in field conditions. An intervention study was defined in Rio Negro Province in Argentina comprising, in total, an area of 5820 Km2. Lambs received two vaccinations with the EG95 vaccine followed by a single booster injection when the animals were 1–1.5 years of age. Vaccination of lambs born into one trial site ..
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