Feasibility and tolerability of bone impact microindentation testing: a cross-sectional, population-based study in Australia
Pamela Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Mark A Kotowicz, Julie A Pasco
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2018
OBJECTIVES: The OsteoProbe measures Bone Material Strength Index (BMSi) of cortical bone in living humans using impact microindentation (IMI). Research using this minimally invasive technique is expanding yet, to-date, there have been no reports about its feasibility in the research setting. In this study, we assessed the feasibility and tolerability of using the OsteoProbe in men enrolled in the Geelong Osteoporosis Study. DESIGN: Cross-sectional analysis of data collected in a population-based study. SETTING: Barwon Statistical Division, southeastern Australia, 2016-2018. METHODS: For 252 of 345 consecutive participants (ages 33-96 years), BMSi was measured using the OsteoProbe at the mid-..View full abstract
Awarded by National health and Medical Research Council (NHMRC)
The Geelong Osteoporosis Study was supported by the National health and Medical Research Council (NHMRC; projects 299831, 628582) and Amgen-GSK OA-ANZBMS, but they played no role in the collection or interpretation of data.