Journal article

Tumour risks and genotype-phenotype correlations associated with germline variants in the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD (vol 55, pg 384, 2018)

KA Andrews, DB Ascher, DE Pires

JOURNAL OF MEDICAL GENETICS | BMJ PUBLISHING GROUP | Published : 2019

Abstract

Andrews KA, Ascher DB, Pires DEV, et al. Tumour risks and genotype-phenotype correlations associated with germline variants in the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD. J Med Genet 2018;55:384-94. doi: 10.1136/jmedgenet-2017-105127. In this paper, Kaplan Meier analysis estimates of the combined penetrance of phaeochromocytoma and paraganglioma (PPGL) and head and neck paraganglioma (HNPGL) was incorrectly reported. This was because of an error importing data into the statistical software R. The following penetrance estimates were affected: The penetrance of PPGL/HNPGL in SDHB non-probands by age 60, reported as '21.8% (95% CI 15.2% to 27.9%)', should read '22.5% (95%CI ..

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