Journal article

The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging

J Kipritidis, BA Tahir, G Cazoulat, MS Hofman, S Siva, J Callahan, N Hardcastle, T Yamamoto, GE Christensen, JM Reinhardt, N Kadoya, TJ Patton, SE Gerard, I Duarte, B Archibald-Heeren, M Byrne, R Sims, S Ramsay, JT Booth, E Eslick Show all

Medical Physics | WILEY | Published : 2019

Abstract

Purpose: CT ventilation imaging (CTVI) is being used to achieve functional avoidance lung cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709, NCT02843568). To address the need for common CTVI validation tools, we have built the Ventilation And Medical Pulmonary Image Registration Evaluation (VAMPIRE) Dataset, and present the results of the first VAMPIRE Challenge to compare relative ventilation distributions between different CTVI algorithms and other established ventilation imaging modalities. Methods: The VAMPIRE Dataset includes 50 pairs of 4DCT scans and corresponding clinical or experimental ventilation scans, referred to as reference ventilation images (RefVIs)..

View full abstract