Journal article
Integrating Genomics into Healthcare: A Global Responsibility
Z Stark, L Dolman, TA Manolio, B Ozenberger, SL Hill, MJ Caulfied, Y Levy, D Glazer, J Wilson, M Lawler, T Boughtwood, J Braithwaite, P Goodhand, E Birney, KN North
American Journal of Human Genetics | CELL PRESS | Published : 2019
Abstract
Genomic sequencing is rapidly transitioning into clinical practice, and implementation into healthcare systems has been supported by substantial government investment, totaling over US$4 billion, in at least 14 countries. These national genomic-medicine initiatives are driving transformative change under real-life conditions while simultaneously addressing barriers to implementation and gathering evidence for wider adoption. We review the diversity of approaches and current progress made by national genomic-medicine initiatives in the UK, France, Australia, and US and provide a roadmap for sharing strategies, standards, and data internationally to accelerate implementation.
Grants
Awarded by Wellcome Trust
Funding Acknowledgements
The Australian Genomics Health Alliance is supported by the Australian National Health and Medical Research Council (GNT1113531). The 100,000 Genomes Project is managed by Genomics England (a wholly owned company of the Department of Health). It is funded by the National Institute for Health Research and NHS England. The Wellcome Trust, Cancer Research UK, and Medical Research Council have also funded research infrastructure. The 100,000 Genomes Project uses data provided by patients and collected by the National Health Service as part of their care and support. M.L. is funded by Health Data Research UK.