Journal article

Adjunctive Peony-Glycyrrhiza decoction for antipsychotic-induced hyperprolactinaemia: a meta-analysis of randomised controlled trials

Wei Zheng, Dong-Bin Cai, Hai-Yan Li, Yu-Jie Wu, Chee H Ng, Gabor S Ungvari, Shan-Shan Xie, Zhan-Ming Shi, Xiao-Min Zhu, Yu-Ping Ning, Yu-Tao Xiang

GENERAL PSYCHIATRY | BMJ PUBLISHING GROUP | Published : 2018

Abstract

Background: Hyperprolactinaemia is a common adverse effect of antipsychotics (APs). The results of Peony-Glycyrrhiza decoction (PGD) as a potentially useful adjunctive treatment for hyperprolactinaemia are inconsistent. Aim: This meta-analysis of randomised controlled trials (RCTs) examined the efficacy and safety of adjunctive PGD therapy for AP-induced hyperprolactinaemia. Methods: English (PubMed, Embase, Cochrane Library, PsycINFO) and Chinese (Chinese National Knowledge Infrastructure, Wanfang Data) databases were systematically searched up to 10 June 2018. The inclusion criteria were based on PICOS-Participants: adult patients with schizophrenia; Intervention: PGD plus APs; Comparison:..

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University of Melbourne Researchers

Grants

Awarded by University of Macau


Awarded by Affiliated Brain Hospital of Guangzhou Medical University


Funding Acknowledgements

The study was supported by the University of Macau (SRG201400019-FHS; MYRG2015-00230 FHS; MYRG2016-00005-FHS) and the Affiliated Brain Hospital of Guangzhou Medical University (2016YFC0906302; 81671334; 2014Y2-00105; 2015BAI13B02). The University of Macau and the Affiliated Brain Hospital of Guangzhou Medical University had no role in the study design, generation or interpretation of the results, and publication of the study.