Journal article

Estimating the prevalence of latent tuberculosis in a low-incidence setting: Australia

KD Dale, JMC Trauer, PJ Dodd, RMGJ Houben, JT Denholm

European Respiratory Journal | EUROPEAN RESPIRATORY SOC JOURNALS LTD | Published : 2018

Abstract

Migration is a key driver of tuberculosis (TB) in many low-incidence settings, with the majority of TB cases attributed to reactivation of latent TB (LTBI) acquired overseas. A greater understanding of LTBI risk in heterogeneous migrant populations would aid health planning. We aimed to estimate the LTBI prevalence and distribution among locally born and overseas-born Australians. Annual risks of TB infection estimates were applied to population cohorts (by country of birth, year of arrival and age) in Australian census data in 2006, 2011 and 2016. Both the absolute number and proportion of Australian residents with LTBI increased from 4.6% (interquartile range (IQR) 4.2-5.2%) in 2006 to 5.1..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

The Miller Foundation funded the Miller Foundation Scholarship for Infection and Immunity, granted to K.D. Dale towards her doctoral studies. P.J. Dodd acknowledges support from the UK Medical Research Council (MR/P022081/1). J.M. Trauer is a recipient of an Early Career Fellowship from the National Health and Medical Research Council. Funding information for this article has been deposited with the Crossref Funder Registry.