Journal article

The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial

Amirsalar Samkani, Mads J Skytte, Christian Anholm, Arne Astrup, Carolyn F Deacon, Jens J Holst, Sten Madsbad, Ray Boston, Thure Krarup, Steen B Haugaard

LIPIDS IN HEALTH AND DISEASE | BMC | Published : 2018

Abstract

BACKGROUND: Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair insulin action and increase risk of cardiovascular disease and death. Dietary carbohydrate reduction has been suggested as non-pharmacological therapy for T2DM, but the acute effects on NEFA and TG during subsequent meals remain to be investigated. METHODS: Postprandial NEFA and TG responses were assessed in subjects with T2DM by comparing a carbohydrate-reduced high-protein (CRHP) diet with a conventional diabetes (CD) diet in an open-label, randomized, cross-over study. Each diet was consumed on two consecutive days, separat..

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University of Melbourne Researchers