Comparison of invasive and non-invasive aortic wave intensity and wave power analyses in sheep

Abstract

Objective: Wave intensity (WI) and wave power (WP) analyses are powerful approaches for assessing ventricular-vascular interactions and arterial dynamics using invasive and non-invasive methods. However, in vivo comparison of these methods for large arteries is lacking. This study assessed agreement, correlation and relative changes in wave size in invasive and non-invasive aortic WI/WP analyses, and associated sources of error. Approach: The proximal descending thoracic aorta (DTA) of nine wethers was instrumented with a micromanometer and perivascular transit-time flow probe to measure high-fidelity blood pressure (P) and flow (Q) for invasive WI/WP analyses at baseline and during haemodyn..