Towards fast and reliable simultaneous EEG-fMRI analysis of epilepsy with automatic spike detection
Amir Omidvarnia, Magdalena A Kowalczyk, Mangor Pedersen, Graeme D Jackson
Clinical Neurophysiology | Elsevier | Published : 2019
Objective The process of manually marking up epileptic spikes for simultaneous electroencephalogram (EEG) and resting state functional MRI (rsfMRI) analysis in epilepsy studies is a tedious and subjective task for a human expert. The aim of this study was to evaluate whether automatic EEG spike detection can facilitate EEG-rsfMRI analysis, and to assess its potential as a clinical tool in epilepsy. Methods We implemented a fast algorithm for detection of uniform interictal epileptiform discharges (IEDs) in one-hour scalp EEG recordings of 19 refractory focal epilepsy datasets (from 16 patients) who underwent a simultaneous EEG-rsfMRI recording. Our method was based on matched filtering of an..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) of Australia
Awarded by NHMRC practitioner fellowship
This work was supported by the National Health and Medical Research Council (NHMRC) of Australia (program grant 1091593). GDJ was supported by an NHMRC practitioner fellowship (1060312). MK was supported by Melbourne Research Scholarship from the University of Melbourne. The Florey Institute of Neuro-science and Mental Health acknowledges the strong support from the Victorian Government and in particular the funding from the Operational Infrastructure Support Grant. The authors acknowledge the facilities, and the scientific and technical assistance of the National Imaging Facility at the Florey Node.