Long-term application of organic fertilization causes the accumulation of antibiotic resistome in earthworm gut microbiota
Jing Ding, Dong Zhu, Bin Hong, Hong Tao Wang, Gang Li, Yi Bing Ma, Yu Ting Tang, Qing Lin Chen
ENVIRONMENT INTERNATIONAL | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019
Antibiotic resistance genes (ARGs), prevalent across multiple environmental media, threaten human health worldwide and are considered emerging environmental contaminants. Earthworm gut, a niche for bacteria to survive, represents a potential reservoir for ARGs in soil. However, the compositions of ARGs in the earthworm gut microbiota remain elusive, especially under field conditions. In this study, we applied high-throughput quantitative PCR to profile the ARGs in the gut microbiota of earthworms after chronic exposure to fertilizers. To elucidate the factors that impact the ARGs composition, the bacterial community of gut microbiota, mobile genetic elements (MGEs), soil (nutrients, heavy me..View full abstract
Awarded by National Natural Science Foundation of China
Awarded by Development Program of China-International collaborative project from Ministry of Science and Technology
This work was funded by the National Natural Science Foundation of China (41807032) and Development Program of China-International collaborative project from Ministry of Science and Technology (Grant No. 2017YFE0107300).