Determinants of social behavior deficits and recovery after pediatric traumatic brain injury
Akram Zamani, Richelle Mychasiuk, Bridgette D Semple
EXPERIMENTAL NEUROLOGY | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2019
Traumatic brain injury (TBI) during early childhood is associated with a particularly high risk of developing social behavior impairments, including deficits in social cognition that manifest as reduced social interactions, with profound consequences for the individuals' quality of life. A number of pre-injury, post-injury, and injury-related factors have been identified or hypothesized to determine the extent of social behavior problems after childhood TBI. These include variables associated with the individual themselves (e.g. age, genetics, the injury severity, and extent of white matter damage), proximal environmental factors (e.g. family functioning, parental mental health), and more di..View full abstract
The authors acknowledge funding support from the National Health and Medical Research Council of Australia (NHMRC) in the form of a Project Grant and Career Development Fellowship to BDS, the Canadian Institute of Health Research (CIHR) in the form of a Project Grant to RM, as well as from Monash University Central Clinical School and the Alberta Children's Hospital Research Institute.