Contemporary Anti-Ebola Drug Discovery Approaches and Platforms
Elena K Schneider-Futschik, Daniel Hoyer, Alexander A Khromykh, Jonathan B Baell, Glenn A Marsh, Mark A Baker, Jian Li, Tony Velkov
ACS Infectious Diseases | AMER CHEMICAL SOC | Published : 2019
The Ebola virus has a grave potential to destabilize civil society as we know it. The past few deadly Ebola outbreaks were unprecedented in size: The 2014-15 Ebola West Africa outbreak saw the virus spread from the epicenter through to Guinea, Sierra Leone, Nigeria, Congo, and Liberia. The 2014-15 Ebola West Africa outbreak was associated with almost 30,000 suspected or confirmed cases and over 11,000 documented deaths. The more recent 2018 outbreak in the Democratic Republic of Congo has so far resulted in 216 suspected or confirmed cases and 139 deaths. There is a general acceptance within the World Health Organization (WHO) and the Ebola outbreak response community that future outbreaks w..View full abstract
Awarded by National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
J.L. and T.V. are supported by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (R01 AI111965). J.L. is an Australian National Health and Medical Research Council (NHMRC) Senior Research Fellow, and T.V. is an Australian NHMRC Industry Career Development Level 2 Research Fellow. D.H. is supported by NHMRC. E.K.S.-F. is an Australian NHMRC Early Career Research Fellow and an appointed Young Ambassador for the American Society of Microbiology (ASM US).