Prospective associations of low muscle mass and strength with health-related quality of life over 10-year in community-dwelling older adults
Saliu Balogun, Tania Winzenberg, Karen Wills, David Scott, Graeme Jones, Michele L Callisay, Dawn Aitken
EXPERIMENTAL GERONTOLOGY | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019
AIMS: This study aims to describe the associations of low muscle mass, handgrip (HGS) and lower-limb muscle strength (LMS) with health-related quality of life (HRQoL) over 10 years in community-dwelling older adults. METHODS: Participants (N = 1002; 51% women; mean age 63 ± 7.4 years) were prospectively followed for 10 years. HRQoL was measured using the validated assessment of quality of life (AQoL) instrument. Appendicular lean mass (ALM) was assessed using dual energy X-ray absorptiometry and normalized to body mass index (BMI). HGS and LMS were assessed using dynamometers. Low ALM/BMI (ALM/BMILOW), LMS (LMSLOW) and HGS (HGSLOW) at baseline were defined as the lowest 20% of the sex-specif..View full abstract
This work was supported by the National Health and Medical Research Council of Australia; Arthritis Foundation of Australia; Royal Hobart Hospital Research Foundation; Tasmanian Community Fund; and University of Tasmania Institutional Research Grants Scheme. Special thanks to the TASOAC participants, staff and volunteers. DS is supported by a National Health and Medical Research Council of Australia Career Development Fellowship (R.D. Wright Biomedical).