Journal article

Life after surgical resection of a meningioma: a prospective cross-sectional study evaluating health-related quality of life

Farshad Nassiri, Benjamin Price, Ameer Shehab, Karolyn Au, Michael D Cusimano, Michael D Jenkinson, Christine Jungk, Alireza Mansouri, Thomas Santarius, Suganth Suppiah, Ken X Teng, Gurvinder S Toor, Gelareh Zadeh, Tobias Walbert, Katharine J Drummond, Kenneth Aldape, Karolyn Au, Jill Barnhartz-Sloan, Wenya Linda Bi, Priscilla K Brastianos Show all

NEURO-ONCOLOGY | OXFORD UNIV PRESS INC | Published : 2019

Abstract

Background: Few studies have evaluated the health-related quality of life (HRQoL) of patients with meningiomas. Here, we report the largest prospective, longitudinal cross-sectional cohort study of HRQoL in meningiomas to date, in order to identify possible actionable determinants of global HRQoL. Methods: Adults who had undergone resection of a grade I intracranial meningioma and were in routine follow-up at a single large tertiary center underwent HRQoL assessment using the QLQ-C30 questionnaire administered opportunistically at follow-up visits. Averaged transformed QLQ-C30 scores at 12-month intervals were compared with scores from a normative reference population, with reference to know..

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