Journal article

The burden of pancreatic cancer in Australia attributable to smoking

Maria E Arriaga, Claire M Vajdic, Robert J MacInnis, Karen Canfell, Dianna J Magliano, Jonathan E Shaw, Julie E Byles, Graham G Giles, Anne W Taylor, Tiffany K Gill, Vasant Hirani, Robert G Cumming, R Paul Mitchell, Emily Banks, Julie Marker, Barbara-Ann Adelstein, Maarit A Laaksonen

MEDICAL JOURNAL OF AUSTRALIA | WILEY | Published : 2019

Abstract

OBJECTIVE: To estimate the burden of pancreatic cancer in Australia attributable to modifiable exposures, particularly smoking. DESIGN: Prospective pooled cohort study. SETTING, PARTICIPANTS: Seven prospective Australian study cohorts (total sample size, 365 084 adults); participant data linked to national registries to identify cases of pancreatic cancer and deaths. MAIN OUTCOME MEASURES: Associations between exposures and incidence of pancreatic cancer, estimated in a proportional hazards model, adjusted for age, sex, study, and other exposures; future burden of pancreatic cancer avoidable by changes in exposure estimated as population attributable fractions (PAFs) for whole population and..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC


Awarded by Cancer Institute NSW


Funding Acknowledgements

We thank the investigators and participants of the participating cohort studies and surveys for providing the data for the cohort consortium. Our investigation was supported by the National Health and Medical Research Council (NHMRC; 1060991). The NHMRC also supported Maarit Laaksonen (I1053642), Karen Canfell (1082989), Emily Banks (1136128), Jonathan Shaw (1079438) and Dianna Magliano (1118161). Maarit Laaksonen was also supported by the Cancer Institute NSW (13/ECF/1-07). Maria Arriaga was supported by an Australian Postgraduate Award and a Translational Cancer Research Network PhD Scholarship Top-up Award.