A Fully Discrete Open Source Framework for the Simulation of Vascular Remodelling.
James M Osbotne, Miguel O Bernabeu
Annu Int Conf IEEE Eng Med Biol Soc | IEEE Explore | Published : 2018
In this paper we present a novel computational framework for the theoretical study of the interaction between haemodynamics and vessel biology, with particular applications to the study of vascular remodelling. We introduce the mathematical formulation, validate the numerical method against an analytical solution derived for a simplified case, and present a case study of tissue remodelling in response to flow.