Diagnostic accuracy of noncontrast CT imaging markers in cerebral venous thrombosis

PJ Buyck; SM Zuurbier; C Garcia-Esperon; MA Barboza; P Costa; I Escudero; D Renard; R Lemmens; N Hinteregger; F Fazekas; JJ Conde; E Giralt-Steinhauer; S Hiltunen; A Arauz; A Pezzini; J Montaner; J Putaala; C Weimar; L Churilov; T Gattringer; H Asadi; T Tatlisumak; JM Coutinho; P Demaerel; V Thijs

Journal article

Diagnostic accuracy of noncontrast CT imaging markers in cerebral venous thrombosis

PJ Buyck, SM Zuurbier, C Garcia-Esperon, MA Barboza, P Costa, I Escudero, D Renard, R Lemmens, N Hinteregger, F Fazekas, JJ Conde, E Giralt-Steinhauer, S Hiltunen, A Arauz, A Pezzini, J Montaner, J Putaala, C Weimar, L Churilov, T Gattringer Show all

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

DOI: 10.1212/WNL.0000000000006959

Abstract

ObjectiveTo assess the added diagnostic value of semiquantitative imaging markers on noncontrast CT scans in cerebral venous thrombosis (CVT).MethodsIn a retrospective, multicenter, blinded, case-control study of patients with recent onset (<2 weeks) CVT, 3 readers assessed (1) the accuracy of the visual impression of CVT based on a combination of direct and indirect signs, (2) the accuracy of attenuation values of the venous sinuses in Hounsfield units (with adjustment for hematocrit levels), and (3) the accuracy of attenuation ratios of affected vs unaffected sinuses in comparison with reference standard MRI or CT angiography. Controls were age-matched patients with (sub)acute neurologic p..

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University of Melbourne Researchers

Leonid Churilov Author

Vincent Thijs Author

Grants

Funding Acknowledgements

The Florey Institute of Neuroscience and Mental Health acknowledges support from the Victorian Government and in particular funding from the Operational Infrastructure Support Grant.