Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Yi Liu; Hyon-Xhi Tan; Marios Koutsakos; Sinthujan Jegaskanda; Robyn Esterbauer; Danielle Tilmanis; Malet Aban; Katherine Kedzierska; Aeron C Hurt; Stephen J Kent; Adam K Wheatley

Journal article

Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Yi Liu, Hyon-Xhi Tan, Marios Koutsakos, Sinthujan Jegaskanda, Robyn Esterbauer, Danielle Tilmanis, Malet Aban, Katherine Kedzierska, Aeron C Hurt, Stephen J Kent, Adam K Wheatley

Nature Communications | NATURE PUBLISHING GROUP | Published : 2019

DOI: 10.1038/s41467-018-08165-y

University of Melbourne Researchers

Robyn Esterbauer Author Microbiology and Immunology

Adam Wheatley Author Microbiology and Immunology

Stephen Kent Author Microbiology and Immunology

Aeron Hurt Author Melbourne School of Population and Global Health

Hyon Xhi Tan Author Microbiology and Immunology

Grants

Awarded by NHMRC programme

Awarded by NHMRC

Funding Acknowledgements

We thank all study participants and the Melbourne Cytometry Platform (MBC node) for expert flow cytometry assistance. This work was supported by NHMRC programme grant ID1052979 (SJK), NHMRC project grant ID1129099 (AKW) and Proof-of-Concept Initiative funding co-provided by the University of Melbourne and Sanofi Pasteur. YL and MK are supported by a Melbourne International Research Scholarship and Melbourne International Fee Remission Scholarship. KK was supported by a NHMRC Senior Research Fellowship Level B. World Health Organization (WHO) Collaborating Centre for Reference Research on Influenza is supported by the Australian Government Department of Health.