Journal article

The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan

Gerben Keijzers, Stephen PJ Macdonald, Andrew A Udy, Glenn Arendts, Michael Bailey, Rinaldo Bellomo, Gabriel E Blecher, Jonathon Burcham, Anthony Delaney, Andrew R Coggins, Daniel M Fatovich, John F Fraser, Amanda Harley, Peter Jones, Fran Kinnear, Katya May, Sandra Peake, David McD Taylor, Julian Williams, Patricia Williams



OBJECTIVE: There is uncertainty about the optimal i.v. fluid volume and timing of vasopressor commencement in the resuscitation of patients with sepsis and hypotension. We aim to study current resuscitation practices in EDs in Australia and New Zealand (the Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis [ARISE FLUIDS] observational study). METHODS: ARISE FLUIDS is a prospective, multicentre observational study in 71 hospitals in Australia and New Zealand. It will include adult patients presenting to the ED during a 30 day period with suspected sepsis and hypotension (systolic blood pressure <100 mmHg) despite at least 1000 mL fluid resus..

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University of Melbourne Researchers


Funding Acknowledgements

This project received funding from the Emergency Medicine Foundation and the Gold Coast Hospital Foundation. The following is the list of participating institutions for the ARISE FLUIDS observational study: New South Wales (20): Auburn Hospital, Bankstown Health Service, Belmont Hospital, Blacktown and Mount Druitt Hospital, Canterbury Hospital, Coffs Harbour Base Hospital, Gosford Hospital, Hornsby Ku-ring-gai Hospital, John Hunter Hospital, Liverpool Hospital, Maitland Hospital, Nepean Hospital, Queanbeyan District Hospital, Royal North Shore Hospital, Royal Prince Alfred Hospital, St Vincent's Hospital, Tamworth Hospital, Wagga Wagga Base Hospital, Westmead Hospital, Wollongong Hospital; New Zealand (9): Auckland City Hospital, Dunedin Hospital, Hawke's Bay Hospital, Middlemore Hospital, Nelson Hospital, Taranaki Base Hospital, Tauranga Hospital, Waikato Hospital, Wellington Hospital; Queensland (18): Bundaberg Base Hospital, Cairns Base Hospital, Gold Coast University Hospital, Hervey Bay Hospital, Logan Hospital, Mackay Base Hospital, Maryborough Hospital, Mount Isa Hospital, Nambour Hospital, The Prince Charles Hospital, Princess Alexandra Hospital, Queen Elizabeth II Jubilee Hospital, Redcliffe Hospital, Robina Hospital, Royal Brisbane and Women's Hospital, Sunshine Coast University Hospital, Toowoomba Hospital, The Townsville Hospital; South Australia (3): Lyell McEwin Hospital, The Queen Elizabeth Hospital, Royal Adelaide Hospital; Tasmania (2): North West Regional Hospital Burnie, Royal Hobart Hospital; Victoria (11): Austin Health, Box Hill Hospital, Cabrini Private Hospital, Casey Hospital, Dandenong Hospital, Epworth Richmond Hospital, Frankston Hospital, Geelong St John of God Hospital, Monash Medical Centre, Royal Melbourne Hospital, The Alfred Hospital; Western Australia (8): Albany Regional Hospital, Armadale-Kelmscott District Memorial Hospital, Broome Hospital, Fiona Stanley Hospital, Nickol Bay Hospital, Midland St John of God Hospital, Rockingham General Hospital, Royal Perth Hospital.